My practical International flying tips (some are potentially abraisive) that work for me:
1) When flying and you are gaining hours (Dubai - London for example) try to sleep on the plane. When flying and losing hours (Vancouver - New York) try to stay awake and arrive tired, but go to bed at a 'normal' time in the new time zone.
2) If you are on a sleeping flight, having 2 cocktails in the departure lounge pretty much guarantees you'll be out like a light as the plane is taking off. (It does me, anyways.)
3) Fly business on long haul flights - especially if you aren't paying for the ticket.
4) If there is a child seated within one row of you on the flight who appears to be under the age of seven, or in the first five minutes of boarding reveals itself to be whiny / snivelly / annoying, ask to be reseated before takeoff. The squeakiest wheel gets the grease here, folks.
5) Earplugs are a travel necessity.
6) The only place you can wear 'Ruben Kincaid' nightshades without being laughed at is on a plane. Take advantage of the opportunity.
7) Avoid the fish dining option, and usually any airline breakfast will be more disgusting than other airline food.
8) Airline food on small, obscure, regional airlines tends to be worse than... well... the buffet at the Stardust for starters.
9) Arrive early to airports, particularly for international flights. You don't want to have to be rushed unnecessarily.
10) Carry US $1 bills (at least 10) for tips / getting rid of annoying people in foreign airports.
11) Bulkhead seats in coach can offer more legroom, but the kid quotient is higher because airliines often put babies in those rows with the fold-out bassinets. Exit rows are good, but on 747's they may also be aligned with the galleys, so can be noisy from stewards/esses rattling around / chatting in there. If stuck in coach, I tend to prefer a window seat and huddle up in a corner making it clear I do not wish to interact with any humans. Second best is an aisle, however I tend to always get bumped and woken up. The back one or two rows can be a good hit - especially if there are any empty seats. Asking to get a row with an empty seat in the middle is great, getting an empty row to yourself is better. If this happens, make sure you take posession of the entire row by spreading out your things as soon as the plane takes off or you may lose it to a 'seat hopper'.