Should Homeopathy be illegal?
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What I know is sufficient for my needs and my needs are not here to excuslively serve your. They serve me enough to make a uniformed judgement on it, i find what I need to know and that suits me fine. I know probably more than you. Anything I have expericned seen or watched is all added into it. I have the side effect illness of a certain drug, its on my medical notes is that scientific enough for you. 
You lept on somthing the side effects and didnt read it all first other wise you would have seen its my own view. I can produce links to in the news medicines, but that wont appease you will it?
http://www.vioxx-celebrex-side-effects.com/html/faqs.html
http://www.medhelp.org/forums/mentalhealth/messages/31068a.html
http://www.soton.ac.uk/~gk/scifi/effects.htm
me and a search engine.
You lept on somthing the side effects and didnt read it all first other wise you would have seen its my own view. I can produce links to in the news medicines, but that wont appease you will it?
http://www.vioxx-celebrex-side-effects.com/html/faqs.html
http://www.medhelp.org/forums/mentalhealth/messages/31068a.html
http://www.soton.ac.uk/~gk/scifi/effects.htm
me and a search engine.
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Why and to what scrutiny of have a differnt level so what level is is assessed by? If there is no level then how can it be justified to demand such like?Flatworm said:
me
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The Pharmaceutical Journal Vol 265 No 7118 p575
October 14, 2000 The Conference
Crookes lecture
Side effects of analgesics can be anticipated from patients' conditions
The adverse effects which patients might experience when using over-the-counter analgesics could be anticipated from a knowledge of patients’ existing conditions, it was explained in a lecture sponsored by Crookes Healthcare given on September 10
The most important risk factor for adverse effects when taking over-the-counter analgesics was the use of concomitant medication, Professor Nicholas Moore (professor of clinical pharmacology, University of Bordeaux, France) said. The condition that the analgesic was being used to treat also had an influence on whether adverse effects might occur.
Professor Moore’s findings were taken from the results of the paracetamol, aspirin and ibuprofen new tolerability (PAIN) study.1 This was a randomised, blinded, parallel-group trial of paracetamol (P), aspirin (A) and ibuprofen (I) administered to patients by French general medical practitioners at doses equivalent to the OTC indications for the products in France at that time. The maximum daily doses were 3g (P or A) or 1.2g (I) to be taken for up to seven days. Patients completed diaries of drug use and adverse effects and were given follow-up calls by their GP after 24 hours and seven to nine days. In total 8,677 patients were randomised (P=2,888; A=2,900; I=2,886). The aim of the trial was to show that ibuprofen was equal to paracetamol and superior to aspirin in terms of tolerability.
Of the patients entering the trial, 99.5 per cent were evaluable and 95 per cent complied with the “rather simple” protocol. This was “almost as good a response as a phase I trial”, Professor Moore said. The most common indications were musculoskeletal pain (33 per cent), colds or influenza (20) and backache (16). Around 25 per cent of patients had concomitant diseases and 45 per cent were taking other medicines during the study.
Looking at the primary end point of the trial, adverse effects were seen in 14.5 per cent (P), 18.5 per cent (A) and 13.7 per cent (I) of patients. This was a significant difference with respect to A and the hypothesis was proven.
“Aspirin had more adverse effects in all categories,” Professor Moore said.
Other risk factors
Presenting a more detailed analysis of the adverse effect profiles from the trial, Professor Moore asked: “So, which patients should we look out for?”
Women had reported more adverse events than men, which could have been because they either complained more or they were, it seemed, more resistant to the action of analgesics, he said.
In terms of age, it was a case of “the older you get the more adverse effects you have”, but Professor Moore noted that “the young complain more than the middle aged”.
Patients with a higher temperature at the start of the trial had fewer adverse events. This might be because patients treating feverish conditions had taken shorter courses of treatment.
The condition which was being treated had an effect on the adverse effect profile. Greater numbers of events were reported when the condition was backache, musculoskeletal pain, headache or “other”.
However, the most important factor was the use of concomitant medication. The greater the number of additional medicines that were being taken the greater was the risk of adverse effects. The greatest risk came if any of the concomitant medicines was “prohibited”, ie, contraindicated on the summary of product characteristics or packaging. This showed that “forbidden medicines were on the label for a good reason” and that OTC analgesics should not be used if they were present.
“The greatest risk of adverse effects with aspirin is in patients with as few as one concomitant medicine. Thus we should not give aspirin to patients taking other drugs,” Professor Moore said. However, when more than three concomitant medicines were being taken then the risk of adverse effects was greater for paracetamol than for aspirin.
In conclusion, Professor Moore said that in common painful conditions, when the product labelling was respected, paracetamol and ibuprofen had equal tolerability.
Aspirin as an analgesic
Answering questions after the lecture, Professor Moore said that when comparing paracetamol and aspirin, then aspirin increased the risk of adverse effects whatever the dose used was. It was not as well tolerated as paracetamol. In his opinion, aspirin should be restricted to use for cardiovascular indications and should no longer be sold over the counter as an analgesic.
Comparing paracetamol and the non-aspirin non-steroidal anti-inflammatory drugs (NANSAIDs), such as ibuprofen, the perception that NANSAIDs were bound to cause more adverse effects was a spill-over from long-term, high-dose studies. This was not applicable to short-term, low-dose use.
“We have indications from the PAIN study that ibuprofen actually has fewer gastrointestinal effects, such as dyspepsia, than paracetamol, which flies in the face of accepted knowledge.”
Asked if the study validated the packaging warnings to “Always read the label”, Professor Moore said that as long as the labelling criteria had been followed the patient population in the study had been perfectly representative of the normal population who purchased OTC analgesics. For example, aspirin sensitivity or asthma had been exclusion criteria for the study.
“Thank God there are pharmacists to help patients read the labels,” he added.
References
Moore N, Van Ganse E, Le Parc J-M, Wall R, Schneid H, Farhan M, et al. The PAIN study: paracetamol, aspirin and ibuprofen new tolerability study. Clin Drug Invest 1999;18: 89-98.
http://www.nassdb.org.uk/f2/Paracetamol_Codeine.htm
God can I stop now. I'm bored
October 14, 2000 The Conference
Crookes lecture
Side effects of analgesics can be anticipated from patients' conditions
The adverse effects which patients might experience when using over-the-counter analgesics could be anticipated from a knowledge of patients’ existing conditions, it was explained in a lecture sponsored by Crookes Healthcare given on September 10
The most important risk factor for adverse effects when taking over-the-counter analgesics was the use of concomitant medication, Professor Nicholas Moore (professor of clinical pharmacology, University of Bordeaux, France) said. The condition that the analgesic was being used to treat also had an influence on whether adverse effects might occur.
Professor Moore’s findings were taken from the results of the paracetamol, aspirin and ibuprofen new tolerability (PAIN) study.1 This was a randomised, blinded, parallel-group trial of paracetamol (P), aspirin (A) and ibuprofen (I) administered to patients by French general medical practitioners at doses equivalent to the OTC indications for the products in France at that time. The maximum daily doses were 3g (P or A) or 1.2g (I) to be taken for up to seven days. Patients completed diaries of drug use and adverse effects and were given follow-up calls by their GP after 24 hours and seven to nine days. In total 8,677 patients were randomised (P=2,888; A=2,900; I=2,886). The aim of the trial was to show that ibuprofen was equal to paracetamol and superior to aspirin in terms of tolerability.
Of the patients entering the trial, 99.5 per cent were evaluable and 95 per cent complied with the “rather simple” protocol. This was “almost as good a response as a phase I trial”, Professor Moore said. The most common indications were musculoskeletal pain (33 per cent), colds or influenza (20) and backache (16). Around 25 per cent of patients had concomitant diseases and 45 per cent were taking other medicines during the study.
Looking at the primary end point of the trial, adverse effects were seen in 14.5 per cent (P), 18.5 per cent (A) and 13.7 per cent (I) of patients. This was a significant difference with respect to A and the hypothesis was proven.
“Aspirin had more adverse effects in all categories,” Professor Moore said.
Other risk factors
Presenting a more detailed analysis of the adverse effect profiles from the trial, Professor Moore asked: “So, which patients should we look out for?”
Women had reported more adverse events than men, which could have been because they either complained more or they were, it seemed, more resistant to the action of analgesics, he said.
In terms of age, it was a case of “the older you get the more adverse effects you have”, but Professor Moore noted that “the young complain more than the middle aged”.
Patients with a higher temperature at the start of the trial had fewer adverse events. This might be because patients treating feverish conditions had taken shorter courses of treatment.
The condition which was being treated had an effect on the adverse effect profile. Greater numbers of events were reported when the condition was backache, musculoskeletal pain, headache or “other”.
However, the most important factor was the use of concomitant medication. The greater the number of additional medicines that were being taken the greater was the risk of adverse effects. The greatest risk came if any of the concomitant medicines was “prohibited”, ie, contraindicated on the summary of product characteristics or packaging. This showed that “forbidden medicines were on the label for a good reason” and that OTC analgesics should not be used if they were present.
“The greatest risk of adverse effects with aspirin is in patients with as few as one concomitant medicine. Thus we should not give aspirin to patients taking other drugs,” Professor Moore said. However, when more than three concomitant medicines were being taken then the risk of adverse effects was greater for paracetamol than for aspirin.
In conclusion, Professor Moore said that in common painful conditions, when the product labelling was respected, paracetamol and ibuprofen had equal tolerability.
Aspirin as an analgesic
Answering questions after the lecture, Professor Moore said that when comparing paracetamol and aspirin, then aspirin increased the risk of adverse effects whatever the dose used was. It was not as well tolerated as paracetamol. In his opinion, aspirin should be restricted to use for cardiovascular indications and should no longer be sold over the counter as an analgesic.
Comparing paracetamol and the non-aspirin non-steroidal anti-inflammatory drugs (NANSAIDs), such as ibuprofen, the perception that NANSAIDs were bound to cause more adverse effects was a spill-over from long-term, high-dose studies. This was not applicable to short-term, low-dose use.
“We have indications from the PAIN study that ibuprofen actually has fewer gastrointestinal effects, such as dyspepsia, than paracetamol, which flies in the face of accepted knowledge.”
Asked if the study validated the packaging warnings to “Always read the label”, Professor Moore said that as long as the labelling criteria had been followed the patient population in the study had been perfectly representative of the normal population who purchased OTC analgesics. For example, aspirin sensitivity or asthma had been exclusion criteria for the study.
“Thank God there are pharmacists to help patients read the labels,” he added.
References
Moore N, Van Ganse E, Le Parc J-M, Wall R, Schneid H, Farhan M, et al. The PAIN study: paracetamol, aspirin and ibuprofen new tolerability study. Clin Drug Invest 1999;18: 89-98.
http://www.nassdb.org.uk/f2/Paracetamol_Codeine.htm
God can I stop now. I'm bored
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Flatworm said:
lost me now completely my source my back logged data on the hardrive several boks and internet oh and my brain. if that s what human I am not dishonest I put up what I found when I looked into it years back and added to it along the way.
I am never dishonest and that statement is untrue how dare you say such a thing tome and suggest tht I am deeply offended by that imeensily.
no I dont know a lot what I do is for my own benefit to help me, I am true to myslef as to others.
NoI dont data lofg every book or article I take waht I need to make my mind up on somthing and as my surgeon suggested it as wellas my docotr I investigated it, I found it didnt provide me particulary well in all ailments. I willnot justify to you my caring side. period.
RichardR
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I saw "a causative relationship could not be proven because of the nature of the study and the small number of patients included."radiating-sunflower said:
Strangely enough I didn't see anything that said ”HALF of all illnesses around are caused by the side effects of modern medicines”.
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Yahzi said:
Sorry to burst you bubble but I typed that out of a book labeld homeopathy , dont tell me what I can or cannot do you have no jurisidiction to do that PERIOD. I will defend what my view is and i feel it works for some and it helped me and that is it just because some leap before looking dont trhrow it back to me.
It works for some people it wrokded for me at a low point, that recipe is a remedy that is how you make a homeopathic remedy and it has an x factor I am sure but seeing as no shops are open I cant go look for it. If it has the orginal substance in it leave unbanned if it hasnt remove it what I said allalong.
I know what I know and so what if i dont practise it I know gardening am I to stop that as I am not a proffessional gardener too? that is what you are saying I also practise cooking I know nothing about that shall I stop ?
Dont anyone ever tell me not to do something i believe in, I belive in it I needed it. I cant be hard and cold as some of you appear to be, Irahter be dead.
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dont be so pendantic on words. you kknow what I meant so lay offRichardR said:
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and I am approaching meltdown. Cynical isnt the be all or end all of life. Being humane to others is.
Learn it.
Learn it.
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No coz when you add them all up I suspect they do tally half.RichardR said:
I'll stick by it it s my won view and I havent seen anything to sway me otherwise.
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no it isnt you may read it like that but it isnt its my own view having recieved that part of modern medicine. Ican lay blame anywhere, I stand my it Its a view my own view until i see somethng that makes me change my mind.RichardR said:
If I wanted to be cynical I would and I dont. that said in angry hurting voiceing.
See, the problem here is that you originally posted your belief as a fact. That doesn't fly well here, if you state something as a fact instead of a belief people want to see what supports your statement and "Uh, well, I think so" isn't going to help you out very much.
RichardR
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Cynical means:radiating-sunflower said:
Hum. didn't se anything about an angry hurting voice. I did see "Negative or pessimistic".
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I said what as a fact? Did I? to FoodbunnyFoodbunny said:
Richardr to you
