Questions about Diabetes?

[Kumar]

Hello all,

I am bit unclear on some aspects related to diabetes & want to clear the same. Frankly, I also want to involve members with biological/medical field/interests in discussions & bit diverting from homeopathy & physics.

My questions about diabetes are:-

1. Is it possible that diabetic medications for increase in insulin levels as oral medicines, injected insulin etc., can cause/result persistant increase in blood sugar levels under certain conditions eg. Pre-diabetic stages, Insulin Resistance etc.?

2. Is there any relation between common salt & blood sugar? Can salt or salty fried snacks taken in excess quantity or accumulated salt can raise blood sugar levels, substancially? Salt & sugar(some other may be as Mg) both seems to be related to water attracting & retaining properties. It has been noted that taking excess salt/salty snacks in excess raises BS levels after 3/6 days (not instantly) & reversed on reducing salt intake. How it can happen?

Best wishes.

 

[Dr. Imago]

1. Is it possible that diabetic medications for increase in insulin levels as oral medicines, injected insulin etc., can cause/result persistant increase in blood sugar levels under certain conditions eg. Pre-diabetic stages, Insulin Resistance etc.?

You already brought this issue up before, and it was already discussed. Please refer back to the previous thread that you started.

2. Is there any relation between common salt & blood sugar?

No.

Can salt or salty fried snacks taken in excess quantity or accumulated salt can raise blood sugar levels, substancially?

No.

Salt & sugar(some other may be as Mg) both seems to be related to water attracting & retaining properties. It has been noted that taking excess salt/salty snacks in excess raises BS levels after 3/6 days (not instantly) & reversed on reducing salt intake. How it can happen?

I think you're confusing blood osmolarity/osmolality, which is predomintately regulated by the kidneys, with the functions of the pancreas and liver which is where blood sugar is regulated. If you're asserting they have an effect on each other, post a reference where you got this information. Otherwise, I have no idea what you are referring to, nor where you got this information. I need a starting point.

-TT

 

[Kumar]

Re: Re: Questions about Diabetes?

You already brought this issue up before, and it was already discussed. Please refer back to the previous thread that you started.

Welcome ThirdTwin. This concept was previously not discussed properly. I think its possibilty was not agreed. But I think it should be again considered.



No.

No
I think you're confusing blood osmolarity/osmolality, which is predomintately regulated by the kidneys, with the functions of the pancreas and liver which is where blood sugar is regulated. If you're asserting they have an effect on each other, post a reference where you got this information. Otherwise, I have no idea what you are referring to, nor where you got this information. I need a starting point.

Frankly, I observed personally that this happens. I herefore wanted to find some relation.

 

[Eos of the Eons]

Oh Bother. Personally observed? How? You have somebody under a microscope? You draw blood and run tests? How?

I rather wonder what your observations are exactly.

 

[Deetee]

Re: Re: Re: Questions about Diabetes?

I herefore wanted to find some relation.

Go get a wife


....or a life - anything that keeps you away from here would do

 

[Badly Shaved Monkey]

It has been noted that taking excess salt/salty snacks in excess raises BS levels after 3/6 days (not instantly) & reversed on reducing salt intake. How it can happen?

Pay attention to the highlighted words.

 

[Sarah-I]

Kumar,

Are you talking about a diabetic who also has renal failure? If they are having to try and follow both a diabetic and a renal diet, then it is very hard.

 

[Zombified]

Oh Bother. Personally observed? How? You have somebody under a microscope? You draw blood and run tests? How?

I rather wonder what your observations are exactly.

Yeah, I kinda gotta chime on that same note, there, Kumar old buddy.

Blood chemistry is a reasonably exact science; all about the numbers as Rolfe would say. Got any?

 

[Badly Shaved Monkey]

Kumar,

Are you talking about a diabetic who also has renal failure? If they are having to try and follow both a diabetic and a renal diet, then it is very hard.

Right. And have you ever seen homeopathy cure renal failure? I doubt it.

 

[Kumar]

BSM,

I do not meant BS increase by carbs & fats in excess snacks as few other carbs & fat not effect much but salty only show effects as I mentioned.

Pls look at this:-

Insulin Resistance

Many scientists believe that insulin resistance is one of the major factors that either allows or causes the components of the metabolic syndrome to develop. The body manufactures insulin to transport sugar (glucose) into cells so they can use it for energy. Obesity worsens insulin resistance, making it increasingly difficult for cells to respond to insulin. The body reacts by releasing more insulin to "override" the insulin resistance. When the body can't produce enough insulin to overcome insulin resistance, blood sugar levels rise, ultimately leading to diabetes.

Although there is no complete agreement yet on the components of the metabolic syndrome or the individual risk levels for each component, we know the syndrome poses a significant health risk to individuals and is a growing health crisis for our country. But there are some steps you can take to reduce the risk posed by each element of the metabolic syndrome.
ADA LINK.

*Insulin resistance is an impaired metabolic response to our body's own insulin so that active muscle cells cannot take up glucose as easily as they should. In that situation, the blood insulin levels are chronically higher which inhibits our fat cells from giving up their energy stores to let us lose weight

Do you feel that bold sentence above are bit unclear?

 

[Zombified]

Do you feel that bold sentence above are bit unclear?

Usually when you cut and paste something, Kumar, it at least contains most of the words of interest. I do not see anything in what you've quoted that has anything whatsoever to do with salt in the diet.

Got those numbers yet?

 

[Benguin]

It has been noted that taking excess salt/salty snacks in excess raises BS levels after 3/6 days (not instantly) & reversed on reducing salt intake. How it can happen?

I always wondered what was raising your BS levels.

 

[Kumar]

Re: Re: Questions about Diabetes?

I always wondered what was raising your BS levels.

Atleast one of 'my mystry' solved.

*snips from ADA Site*

The cause of diabetes continues to be a mystery, although both genetics and environmental factors such as obesity and lack of exercise appear to play roles.

There are 18.2 million people in the United States, or 6.3% of the population, who have diabetes. While an estimated 13 million have been diagnosed with diabetes, unfortunately, 5.2 million people (or nearly one-third) are unaware that they have the disease.

Unlike some traits, diabetes does not seem to be inherited in a simple pattern. Yet clearly, some people are born more likely to get diabetes than others.

Type 1 and type 2 diabetes have different causes. Yet two factors are important in both. First, you must inherit a predisposition to the disease. Second, something in your environment must trigger diabetes.

Genes alone are not enough. One proof of this is identical twins. Identical twins have identical genes. Yet when one twin has type 1 diabetes, the other gets the disease at most only half the time. When one twin has type 2 diabetes, the other's risk is at most 3 in 4.


In contrast, people who live in areas that have not become Westernized tend not to get type 2 diabetes, no matter how high their genetic risk.

Obesity is a strong risk factor for type 2 diabetes. Obesity is most risky for young people and for people who have been obese for a long time.
( Is It not diabetes(IR) a strong risk factor for Obesity)
--------
What is insulin resistance?
Insulin resistance occurs when the normal amount of insulin secreted by the pancreas is not able to unlock the door to cells. To maintain a normal blood glucose, the pancreas secretes additional insulin. In some cases (about 1/3 of the people with insulin resistance), when the body cells resist or do not respond to even high levels of insulin, glucose builds up in the blood resulting in high blood glucose or type 2 diabetes. Even people with diabetes who take oral medication or require insulin injections to control their blood glucose levels can have higher than normal blood insulin levels due to insulin resistance.

Why is insulin resistance in the news?
More and more people in the U.S. are becoming obese, physically inactive, or both. Obesity and physical inactivity aggravate insulin resistance [? it may be opposite] .Also, people who are insulin resistant typically have an imbalance in their blood lipids (blood fat). They have an increased level of triglycerides (blood fat) and a decreased level of HDL (good) cholesterol. Imbalances in triglycerides and HDL cholesterol increase the risk for heart disease. These findings have heightened awareness of insulin resistance and its impact on health. [? may be as a result of hyperinsulinemia due to excess medication so IR]
http://syndromex.stanford.edu/InsulinResistance.htm

Pls look at bold ones & my suspicions in [].

 

[Zombified]

Dude, I'm still not seeing the salt connection. What's up with that? Salt does not cause obesity, either.

 

[Carn]

[

2. Is there any relation between common salt & blood sugar?

Trying to be a hipocrit, shouldn't the answer not be "no", but "not in any way thats observable for you and not as long as the dosis is not far more than normal daily salt dosis"?

I mean, is anyone certain, that after taking a lethal dosis of salt, the blood sugar level does not change in the process of dying?

Carn

 

[Kumar]

Dude, I'm still not seeing the salt connection. What's up with that? Salt does not cause obesity, either.

Salt-Sugar levels relation is not indicated directly. Let us try to look indirectly:

1. Whether salt effects digetive pH, which may enhance high carbs/fat digestion & absorption?

2. Whether salt absorb/suck internal water from intestine which can make the stool soft?

3. Whether salt/sodium plays some role in absorption & transportation of sugar/fats molecules across intestines?

4. Exess absorbed salt may result high BP, edema (also lower acidity? not sure)--- all may so lead to mental stress & infections. Whether mental stress & infections raises BS level or not?

5. Whether excess thirst & urine linked to salt imbalances?

6. Under homeostatis: salt/sodium is linked to Potassium>Calcium>Magnesium.., how imbalances in these due to imbalance in salt/sodium can effect BS levels?

Pls try to remember/think dynamically or differantly.

 

[The Don]

And I presume that you woud insist that the symptoms of salt poisoning would be replicated when you take homoeopathic dilutions of tissue salts, Yes ?

Your BS levels are clearly very high.

 

[Kumar]

Absorption of Glucose: Transport Across the Intestinal Epithelium
Absorption of glucose, or any molecule for that matter, entails transport from the intestinal lumen, across the epithelium and into blood. The transporter that carries glucose and galactose into the enterocyte is the sodium-dependent hexose transporter, known more formally as SGLUT-1. As the name indicates, this molecule transports both glucose and sodium into the cell and in fact, will not transport either alone.

The essence of transport by the sodium-dependent hexose transporter involves a series of conformational changes induced by binding and release of sodium and glucose, and can be summarized as follows:

the transporter is initially oriented facing into the lumen - at this point it is capable of binding sodium, but not glucose


sodium binds, inducing a conformational change that opens the glucose-binding pocket


glucose binds and the transporter reorients in the membrane such that the pockets holding sodium and glucose are moved inside the cell


sodium dissociates into the cytoplasm, causing glucose binding to destabilize


glucose dissociates into the cytoplasm and the unloaded transporter reorients back to its original, outward-facing position
http://arbl.cvmbs.colostate.edu/hbooks/pathphys/digestion/smallgut/absorb_sugars.html
------
carbohydrate absorption


Carbohydrate absorption tends to occur at the small intestine brush border:

fructose:
absorbed passively down a concentration gradient
binds to a specific carrier protein in the apical cell membrane
either:
diffuses passively out of cells and into capillaries
forms lactate which then diffuses into portal blood

glucose:
absorbed mainly in jejunum by active process
enters via a co-transporter protein on the apical side of the enterocyte
co-transporter requires presence of sodium ions
sodium ions pass down electrochemical gradient into cell to replace sodium ions which are actively being transported out of cell on basolateral membrane by Na+/K+ ATPase pump
glucose diffuses out of cell into intercellular space and from there to local capillaries
chloride ions and water accompany the movement of sodium and glucose; they may travel through the cell or through the intercellular space

galactose: absorbed by a similar sodium-dependent co-transporter as glucose
The dependence of water and salt absorption on the absorption of glucose is the reason why oral rehydration solutions contain all three components.
http://www.gpnotebook.co.uk/cache/818937895.htm

------

....Disruption of carbohydrate absorption


1. Deficiency in brush border enzymes lactase deficiency is either congenital or acquired later in life - most common

maltase deficiency is not known

2. GI infection/disease,coeliac disease, bacterial infections, protazoan infections can all cause inflammation and interference with brush border absorption


Consequence of poor carbohydrate absorption - osmotic diarrhoea LINK

Can you check sodium/sugar relation ? Edited end one as too long. Pls read LINK.

 

[Sarah-I]

BSM,

Homeopathy has nothing at all to do with this. Did you hear me mention it?

The answer to your question is NO by the way.

Kumar,

Insulin resistance, as well as being part of diabetes is also thought to be part of PCOS (Polycystic Ovarian Syndrome). A lot of women who suffer from this syndrome are given the drug Metformin as treatment, as it is felt that the causation is insulin resistance, so treating the insulin resistance might help in these cases. However, not all people with insulin resistance are diabetic.

 

[Rolfe]

Important question about diabetes.

This is the first (or one of the first) threads Kumar started the first day he came here. You can see we've gone right back to square 1. You can also see how little note Kumar has taken of anything anyone told him.

Kumar has an agenda here, as always. This time, he believes he has made some sort of observation about diabetes based on the case of his "friend" (now confirmed to be Kumar himself), which all the diabetologists in the world have missed. He believes it is his duty to alert science and medicine to his great discovery, so that the wrong treatment they have been giving up till now can be corrected. To be more specific, he's utterly convinced that excess insulin administration can cause insulin resistance. And no amount of contrary evidence will sway him at all.

Can anybody spell "hubris"?

So that's what you're in for. More and more pages where the medics carefully explain the very well-understood biochemistry of type II diabetes to Kumar, and try to understand his virtually undocumented observations and irrational conclusions. And Kumar flatly rejects all information that might suggest he's not quite got the right end of the stick.

That's all. Carry on, folks.

Rolfe.