Chris Haynes
Perfectly Poisonous Person
Somewhat related....They had the author of "1491" on the Diane Rehm show this morning. The brunt of the book (apparently, I havn't read it yet) is that the population of the Americas was much larger than previously thought, that many of the civilizations were considerably more advanced than is commonly represented in textbooks, and that as many as 9 out of 10 of these peoples may have been killed by European-borne diseases.....
One book that I have read that addresses that is Plagues and Peoples:
http://www.amazon.com/gp/product/0385121229/103-6373895-1211035?v=glance&n=283155&n=507846&s=books&v=glance ... I remember something about 95% of the native American population was wiped out between 1500 and 1800 (or was it 1700?).
Some of this is addressed in Jared Diamond's Guns, Germs and Steel.
I do not have a reference for this, but I lived in Caracas, Venezuela in the 5th and 6th grades. In my school (an American school, http://www.eca.com.ve/ ) we had a teacher come in everyday to teach Venezuelan history and social studies (usually in the form of some great story telling). Some of the history included what the Conquistadores did to the native population (some of it is described in Diamond's book). The Spanish did exactly what the name "conquistador" implied... conquered. Not only with guns but with large dogs (the teacher described how they were trained to attack human throats). The Spanish also used the native population for slave labor... but since they managed to wipe out most of the Carib population, they had to import slaves from Africa.
I have recently read some books on the "Buffalo Soldiers". These were black soldiers in segregated units created after the American Civil War... they were sent to the Western Frontier. Some of their duties were to chase down and hunt Indians. I read more than one book on the subject, but I cannot remember any that were any good (they were mostly dreadful historical tomes... great stories that need to be written by someone who can WRITE!!!). Interest in that was from visiting the Army Museum near where my parents live: http://huachuca-www.army.mil/HISTORY/huachuca.htm
Locally to me now, the European diseases had pretty much dessimated the population prior to any long lasting contact. I read that the English ships (Vancouver) that came to Puget Sound noted smallpox scars on the Indians. More recently entire tribes would be forced to move when profitable mines were found... lots of stuff here:
http://content.lib.washington.edu/aipnw/index.html (there is enough stuff in there to keep you busy for a L..O..N..G time)