A Cool Way to a Long Life
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Caloric dietary restriction prolongs life span in a variety of organisms, and in mammals the resultant lowering of core body temperature has been offered as one potential explanation. Conti et al. (p. 825; see the Perspective by Saper) generated transgenic mice that overexpress mitochondrial uncoupling protein 2 in hypocretin-producing neurons within the hypothalamus, which lowers core body temperature by about 0.5°C. In the absence of caloric restriction, the median life span of these "cool mice" was about 15% greater than that of their wild-type littermates.
Predicting Changes in Biodiversity
Predicting the effects of environmental change on biodiversity requires an understanding of whether those changes will affect which species occupy a given site, as well as their relative prevalence. Shipley et al. (p. 812, published online 5 October; see the Perspective by McGill) developed a quantitative method based on plant traits to answer these questions and test its effectiveness on a data set from a 42-year process of secondary succession after agricultural abandonment of sites in southern France. Their method successfully predicts community composition and relative abundance with a high level of accuracy.
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Thanks!!
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